TL;DR looks like yes, but I don’t know the extent
I don’t know much detail about how Tor Browser works, but checking devicePixelRatio in console shows that it’s always at 2. So perhaps there is some protection in this regard?
But you do have to remember that zoom level indirectly affects your screen size as it appears to the website (size on the monitor remains unchanged, but there are fewer pixels fitting into the view), and I believe even the “Safest” setting can’t save you from that because media queries can be used to detect screen size: